Search results for "Cerebral aneurysms"

showing 3 items of 3 documents

Multimodal Intraoperative Neuromonitoring in Aneurysm Surgery

2017

Following aneurysmal subarachnoid hemorrhage, the primary goal of treatment is to exclude the vascular malformation from the intracranial circulation, while preserving the parent artery. In unruptured aneurysms, the decision whether to treat or observe the malformation is made on a case-by-case basis. In this regard, the ISUIA (International Study of Unruptured Intracranial Aneurysms) investigators suggested that aneurysm size and location were independent predictors for aneurysm rupture.1 ISUIA examined 1692 patients with cerebral aneurysms with a mean follow-up time of 4.1 years. Rupture rates differed depending on size and location, ranging from 0% in aneurysms <7 mm located in the in…

International Subarachnoid Aneurysm Trialmedicine.medical_specialtyMonitoringSomatosensoryPostoperative deficits03 medical and health sciences0302 clinical medicineAneurysmmedicineHumansCerebral aneurysms; Intraoperative monitoring; Postoperative deficits; Somatosensory evoked potentials; Transcranial motor evoked potentials; Aneurysm; Humans; Monitoring Intraoperative; Evoked Potentials Motor; Evoked Potentials Somatosensory; Surgery; Neurology (clinical)Cerebral aneurysmsEvoked PotentialsIntraoperative monitoringSomatosensory evoked potentialsIntraoperativebusiness.industryMultimodal Intraoperative Neuromonitoring in Aneurysm Surgerymedicine.diseaseAneurysmSurgeryCerebral aneurysms Intraoperative monitoring Postoperative deficits Somatosensory evoked potentials Transcranial motor evoked potentialsMotorSomatosensory evoked potential030220 oncology & carcinogenesisAnesthesiaAneurysm surgerySurgeryNeurology (clinical)businessTranscranial motor evoked potentials030217 neurology & neurosurgery
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Serum Amyloid A Is Present in Human Saccular Intracranial Aneurysm Walls and Associates With Aneurysm Rupture

2021

AbstractSaccular intracranial aneurysm (sIA) rupture leads to a disabling subarachnoid hemorrhage. Chronic inflammation and lipid accumulation in the sIA wall contribute to wall degenerative remodeling that precedes its rupture. A better understanding of the pathobiological process is essential for improved future treatment of patients carrying sIAs. Serum amyloid A (SAA) is an acute-phase protein produced in response to acute and chronic inflammation and tissue damage. Here, we studied the presence and the potential role of SAA in 36 intraoperatively resected sIAs (16 unruptured and 20 ruptured), that had previously been studied by histology and immunohistochemistry. SAA was present in all…

MECHANISMPathologybiomarkkeritAneurysm Ruptured3124 Neurology and psychiatrychemistry.chemical_compoundverisuonitaudit0302 clinical medicineMedicineapolipoproteiinitSerum Amyloid A Protein0303 health sciencesbiologytulehdusaneurysmaINDUCTIONGeneral MedicineC-REACTIVE PROTEINSAANeurologyMyeloperoxidaseImmunohistochemistryInflammation Mediatorsmedicine.symptomSaccular intracranial aneurysmEXPRESSIONmedicine.medical_specialtySubarachnoid hemorrhagelipoproteiinitProstaglandinInflammationLDLPathology and Forensic MedicineLIPOPROTEINS03 medical and health sciencesCellular and Molecular NeuroscienceAneurysmHUMAN MAST-CELLSHumansSerum amyloid Akallonsisäinen aneurysma030304 developmental biologyInflammationSerum Amyloid A Proteinbusiness.industry3112 NeurosciencesIntracranial AneurysmCEREBRAL ANEURYSMS3126 Surgery anesthesiology intensive care radiologymedicine.diseaseAneurysmchemistryDENSITYbiology.proteinEndothelium Vascular3111 BiomedicineNeurology (clinical)business030217 neurology & neurosurgerySerum amyloid A
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SPH modeling of blood flow in cerebral aneurysms

Gli aneurismi cerebrali sono dilatazioni patologiche di arterie cerebrali. Queste patologie hanno un intrinseco rischio di rottura con conseguenti emorragie intracraniche. Sebbene i meccanismi di formazione, crescita e rottura degli aneurismi cerebrali non sono ancora del tutto compresi, è comunemente riconosciuto che in questi processi i fattori emodinamici giocano un ruolo molto importante. Le simulazioni numeriche possono fornire utili informazioni sull'emodinamica e possono essere usate per applicazioni cliniche. Nei tradizionali metodi numerici basati su una griglia di calcolo il processo di discretizzazione dei vasi cerebrali sui quali insiste un aneurisma è molto complesso. D’altra p…

mechanical platelet activationSmoothed particle hydrodynamics (SPH)parallel computingHemodynamicsMulti-blockOpen-boundariescerebral aneurysmsPressure Poisson EquationSettore ICAR/01 - Idraulica
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